Did You Know?

In March of 2010, the FDA put a warning on the Plavix (clopidogrel) product insert that patients with a certain DNA variation of CYP2C19 (pronounced sip-2C19) were at high risk of treatment failure resulting in major cardiac problems or even death.

CYP2C19 is not just involved in Plavix metabolism, it is involved in the metabolism of ~10% of medications.

Other common medications processed by CYP2C19 include:
· voriconazole
· Prilosec
· Prevacid
· Aciphex
· Nexium
· Soma
· Lexapro
· Silenor
· Dexilant